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一种来自诺卡氏菌属海洋来源细菌的新型环肽。

A new cyclic peptide from a marine-derived bacterium of the genus Nocardiopsis.

作者信息

Shin Jongheon, Seo Youngwan, Lee Hyi-Seung, Rho Jung-Rae, Mo Sang Jun

机构信息

Natural Products Research Institute, College of Pharmacy, Seoul National University, #28 Yungun, Jongro, Seoul 110-460, Korea.

出版信息

J Nat Prod. 2003 Jun;66(6):883-4. doi: 10.1021/np030075r.

Abstract

A new cyclic tetrapeptide (1) was isolated from the culture broth of an actinomycete of the genus Nocardiopsis collected from the Pacific deep-sea sediment. The structure of this compound was determined to be cyclo-(L-isoleucyl-L-prolyl-L-leucyl-L-prolyl) on the basis of combined chemical and spectral methods.

摘要

从采集自太平洋深海沉积物的诺卡氏放线菌属放线菌的培养液中分离出一种新的环状四肽(1)。基于化学和光谱方法相结合,确定该化合物的结构为环-(L-异亮氨酰-L-脯氨酰-L-亮氨酰-L-脯氨酰)。

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