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抗心磷脂抗体与脑血管疾病关系的研究

Study on relationship between anticardiolipin antibody and cerebrovascular diseases.

作者信息

Liu C, Xia Y, Sun S, Yuan G, Tong E

机构信息

Department of Neurology, Xiehe Hospital, Tongji Medical University, Wuhan 430022.

出版信息

J Tongji Med Univ. 1999;19(1):59-62. doi: 10.1007/BF02895599.

DOI:10.1007/BF02895599
PMID:12840879
Abstract

Serum anticardiolipin antibody (ACA) was measured in 91 patients with cerebral infarction (CI), 42 patients with cerebral hemorrhage (CH) and 30 healthy controls. The results showed that the ACA in CI and CH patients was significantly higher than in controls and IgG-ACA was the most important isotype. Stroke in ACA positive group tended to be recurrent and of multi-focuses. Positive rate of IgG-ACA reached its peak within the first week after stroke onset. The results suggested that ACA was an independent risk factor in CI and CH and might be valuable in stroke prediction.

摘要

对91例脑梗死(CI)患者、42例脑出血(CH)患者和30名健康对照者检测了血清抗心磷脂抗体(ACA)。结果显示,CI和CH患者的ACA显著高于对照组,且IgG-ACA是最重要的同种型。ACA阳性组的卒中倾向于复发且为多灶性。IgG-ACA阳性率在卒中发作后的第一周内达到峰值。结果表明,ACA是CI和CH的独立危险因素,可能对卒中预测有价值。

相似文献

1
Study on relationship between anticardiolipin antibody and cerebrovascular diseases.抗心磷脂抗体与脑血管疾病关系的研究
J Tongji Med Univ. 1999;19(1):59-62. doi: 10.1007/BF02895599.
2
Anticardiolipin antibodies in an unselected stroke population.未经过筛选的中风人群中的抗心磷脂抗体。
Lancet. 1994 Aug 13;344(8920):452-6. doi: 10.1016/s0140-6736(94)91775-2.
3
Anticardiolipin antibodies are not an independent risk factor for stroke: an incident case-referent study nested within the MONICA and Västerbotten cohort project.抗心磷脂抗体并非中风的独立危险因素:一项纳入莫尼卡(MONICA)研究及韦斯特博滕队列项目的病例对照研究。
Stroke. 2000 Jun;31(6):1289-93. doi: 10.1161/01.str.31.6.1289.
4
Importance of serum anticardiolipin antibody levels in coronary heart disease.
Clin Cardiol. 1994 Mar;17(3):117-21. doi: 10.1002/clc.4960170304.
5
Cardiolipin antibodies and lupus anticoagulant in young patients with a cerebrovascular accident in the past.既往有脑血管意外的年轻患者中的心磷脂抗体和狼疮抗凝物。
Neth J Med. 1993 Apr;42(3-4):93-8.
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Association of periprocedural neurological deficit in carotid stenting with increased anticardiolipin antibodies.
Thromb Res. 2009 Apr;123(6):827-31. doi: 10.1016/j.thromres.2008.08.007. Epub 2008 Sep 24.
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The role of persistent anticardiolipin antibody as risk factor of ischemic stroke.持续性抗心磷脂抗体作为缺血性中风危险因素的作用。
Acta Med Indones. 2005 Oct-Dec;37(4):205-9.
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Anticardiolipin antibodies in acute non-hemorrhagic stroke seen within six hours after onset.急性非出血性卒中发病后6小时内的抗心磷脂抗体
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9
[Comparative study of the occurrence of beta-2-glycoprotein I antibodies (anti-beta-2-GPI) and anticardiolipin antibodies (ACA) in the blood of pregnant women].孕妇血液中β2糖蛋白I抗体(抗β2-GPI)和抗心磷脂抗体(ACA)发生率的比较研究
Ceska Gynekol. 1999 Jul;64(4):255-61.
10
[Anticardiolipin antibody in cerebral infarction].[脑梗死中的抗心磷脂抗体]
Rinsho Shinkeigaku. 1991 Apr;31(4):391-5.

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Lancet. 1994 Aug 13;344(8920):452-6. doi: 10.1016/s0140-6736(94)91775-2.
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