Mosli Hisham A
Department of Urology, King Abdul-Aziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia. hmosli@ hotmail.com
Saudi Med J. 2003 Jun;24(6):573-81.
Epidemiologic studies revealed that there are variations in the geographic and ethnic distribution of cancer of the prostate (CaP) gland. This cancer varies dramatically between being very common in black American men, to rare in Asian and Chinese men. Genetic, familial predisposition and environmental factors in addition to methods of cancer detection and reporting contribute to these variations. Prostate cancer is the ninth most commonly diagnosed cancer in the world yet it ranks first in the United States of America (USA) where resources allow large epidemiological studies. The health policy makers take major decisions such as mass population screening according to data derived from such studies that include information on disease specific mortality rates and incidence rates for each of the ethnic sub-populations living in the USA. Until now, we do not have similar information in the Kingdom of Saudi Arabia (KSA); therefore, policy decisions should consider the possibility of the difference in situations since genetic, familial and environmental conditions are different. Our current local data, although little, indicates that prostate cancer occurs at a lower incidence rate than western countries. The objective of this article is to provide all the available information on the different aspects of CaP gland in KSA. A second more important objective is to attract the attention of the future expectations that need preparation since the possibility of disease prevention does exist.
流行病学研究表明,前列腺癌(CaP)的地理分布和种族分布存在差异。这种癌症在黑人美国男性中非常常见,而在亚洲和中国男性中则很少见,差异极大。除了癌症检测和报告方法外,遗传、家族易感性和环境因素也导致了这些差异。前列腺癌是世界上第九大最常被诊断出的癌症,但在美国(USA)它排名第一,因为美国有资源进行大规模的流行病学研究。卫生政策制定者根据此类研究得出的数据做出重大决策,例如大规模人群筛查,这些数据包括生活在美国的每个种族亚人群的疾病特异性死亡率和发病率信息。到目前为止,沙特阿拉伯王国(KSA)还没有类似的信息;因此,由于遗传、家族和环境条件不同,政策决策应考虑情况差异的可能性。我们目前的本地数据虽然很少,但表明前列腺癌的发病率低于西方国家。本文的目的是提供沙特阿拉伯王国前列腺癌不同方面的所有可用信息。第二个更重要的目的是引起对未来预期的关注,因为疾病预防是有可能的,所以需要做好准备。