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为何伦敦人缺血性心脏病和中风的死亡率较低。

Why Londoners have low death rates from ischaemic heart disease and stroke.

作者信息

Barker D J, Osmond C, Pannett B

机构信息

MRC Environmental Epidemiology Unit, Southampton General Hospital, University of Southampton.

出版信息

BMJ. 1992;305(6868):1551-4. doi: 10.1136/bmj.305.6868.1551.

DOI:10.1136/bmj.305.6868.1551
PMID:1286384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1884723/
Abstract

OBJECTIVE

To explain the low death rates from cardiovascular disease in London.

SETTING

London and the other counties of England and Wales.

SUBJECTS

Women living in London during 1901-10 and people in London dying during 1968-78.

RESULTS

At the beginning of the twentieth century young women aged 15-34 in London had remarkably low death rates, largely because of low rates for tuberculosis and other infectious diseases and low mortality during childbirth. Their low death rates contrasted with the high rates in girls under 15 years.

CONCLUSIONS

Large numbers of young women had migrated into London from agricultural counties in southern England and went into domestic service, where the diet was usually very good. Recent findings suggest that a mother's nutrition and health has a major effect on the risk of cardiovascular disease in the next generation. The low cardiovascular mortality in London is consistent with this, and contrasts with the high mortality from other common diseases.

摘要

目的

解释伦敦心血管疾病死亡率较低的原因。

背景

伦敦以及英格兰和威尔士的其他郡。

研究对象

1901年至1910年间居住在伦敦的女性以及1968年至1978年间在伦敦死亡的人群。

结果

在20世纪初,伦敦15至34岁的年轻女性死亡率极低,这主要是因为结核病和其他传染病的发病率低以及分娩死亡率低。她们的低死亡率与15岁以下女孩的高死亡率形成对比。

结论

大量年轻女性从英格兰南部的农业郡迁入伦敦并从事家政服务,在家政服务中她们的饮食通常非常好。最近的研究结果表明,母亲的营养和健康状况对下一代患心血管疾病的风险有重大影响。伦敦较低的心血管疾病死亡率与此相符,并且与其他常见疾病的高死亡率形成对比。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6129/1884723/b6508da0dc00/bmj00105-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6129/1884723/b6508da0dc00/bmj00105-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6129/1884723/b6508da0dc00/bmj00105-0046-a.jpg

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J Epidemiol Community Health. 1997 Apr;51(2):121-6. doi: 10.1136/jech.51.2.121.
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Mortality from cardiovascular disease among interregional migrants in England and Wales.英格兰和威尔士地区间移民的心血管疾病死亡率。
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