Leung Harry, Wang Jie Jin, Rochtchina Elena, Tan Ava G, Wong Tien Y, Hubbard Larry D, Klein Ronald, Mitchell Paul
Centre for Vision Research, Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia.
Clin Exp Ophthalmol. 2003 Aug;31(4):326-30. doi: 10.1046/j.1442-9071.2003.00661.x.
This study assessed the correlation between computer-assisted retinal vessel measurements of right and left eyes, from subjects in a defined, community-based older population. Retinal photographs from participants in the Blue Mountains Eye Study were digitized. All retinal arterioles and venules located 0.5-1.0 disc diameters from the optic disc margin were identified and a computer program measured their diameters. Pearson correlation (R2) statistic was used to assess the correlation in a random subsample of 1546 images. Substantial correlation between right and left eye measurements was found for summary indices of retinal arterioles (R2 = 0.70) and venules (R2 = 0.77). Higher correlation was found for intragrader (R2 0.75-079) than for intergrader assessment (R2 0.67-0.72). Moderate correlation was found in arteriole-to-venule ratio assessed by the same (R2 = 0.57) or different (R2 = 0.52) graders. Measurements from one eye can thus adequately represent the retinal vessel diameters of a person.
本研究评估了特定社区老年人群中左右眼计算机辅助视网膜血管测量值之间的相关性。对蓝山眼研究参与者的视网膜照片进行了数字化处理。识别出所有位于距视盘边缘0.5 - 1.0视盘直径处的视网膜小动脉和小静脉，并用计算机程序测量其直径。采用Pearson相关（R2）统计量评估1546幅图像随机子样本中的相关性。结果发现，视网膜小动脉（R2 = 0.70）和小静脉（R2 = 0.77）的汇总指标在左右眼测量值之间存在显著相关性。分级者内部（R2 0.75 - 0.79）的相关性高于分级者之间（R2 0.67 - 0.72）。由同一位分级者（R2 = 0.57）或不同分级者（R2 = 0.52）评估的动静脉比存在中度相关性。因此，一只眼睛的测量值能够充分代表一个人的视网膜血管直径。
