Hulette Christine M
Duke University Medical Center, Department of Pathology, Durham, North Carolina 27710, USA.
J Neuropathol Exp Neurol. 2003 Jul;62(7):715-22. doi: 10.1093/jnen/62.7.715.
Many of us who conduct research based on disorders that uniquely affect the human nervous system are involved directly or indirectly with brain banks. Brain banking is by its very nature a multi-disciplinary endeavor that requires close collaboration with our colleagues in clinical departments and also with the families and patients who are donors of brain tissue. These brain tissues will ultimately be used for many types of basic science investigations. Thus, many brain banks are as unique as the basic research programs that they serve. However, there are some commonalities in the field of brain banking. This paper represents a broad overview of brain banking and the issues that are common to all brain banks. Legal and ethical concerns regarding confidentiality of donor records and donor recruitment procedures, as well as safety precautions for technical staff, tissue banking methods and disbursement will be discussed. Finally, issues surrounding financial support for brain banks will be considered.
我们当中许多基于独特影响人类神经系统的疾病开展研究的人，都直接或间接地参与了脑库工作。脑库工作本质上是一项多学科的努力，需要与临床科室的同事以及脑组织捐赠者的家属和患者密切合作。这些脑组织最终将用于多种类型的基础科学研究。因此，许多脑库就像它们所服务的基础研究项目一样独特。然而，脑库领域存在一些共性。本文对脑库及其所有脑库共有的问题进行了广泛概述。将讨论有关捐赠者记录保密和捐赠者招募程序的法律和伦理问题，以及技术人员的安全预防措施、组织库方法和分发问题。最后，将考虑围绕脑库资金支持的问题。
