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用于伤口冲洗的温热生理盐水与室温生理盐水对比:一项随机临床试验

Warmed versus room temperature saline for laceration irrigation: a randomized clinical trial.

作者信息

Ernst Amy A, Gershoff Leslie, Miller Penny, Tilden Elizabeth, Weiss Steven J

机构信息

Division of Emergency Medicine, University of California at Davis Medical Center, Sacramento, CA 95817, USA.

出版信息

South Med J. 2003 May;96(5):436-9. doi: 10.1097/01.SMJ.0000056657.63336.6C.

Abstract

BACKGROUND

Patient comfort is an important part of laceration repair.

METHODS

The study was a randomized single-blind cross-over trial in which each participant received 250 ml warmed and 250 ml room temperature saline irrigation in simple linear wounds after a local anesthetic was instilled. The solutions and the order of irrigation (warmed first versus second) were separately randomized with a washout period between. Investigators obtaining scores were blinded. Participants determined preferred solution, whether the solution was soothing, and which caused the most discomfort. Participants rated the pain of irrigation using separate Visual Analog Scale scores.

RESULTS

Thirty-eight patients were enrolled in the study. Significantly more preferred warmed to room temperature solutions (difference, 34%; 95% confidence interval, 5.7-63). A Wilcoxon signed-rank test for paired data showed no order effect (P = 0.49) or difference in pain measured according to the Visual Analog Scale (P = 0.082).

CONCLUSION

Warmed saline was more comfortable and soothing than room temperature saline as a wound irrigant among patients with linear lacerations.

摘要

背景

患者舒适度是裂伤修复的重要组成部分。

方法

本研究为随机单盲交叉试验,在局部麻醉剂注入后,每位参与者在简单线性伤口中分别接受250毫升温热盐水和250毫升室温盐水冲洗。溶液和冲洗顺序(先温热与后温热)分别随机分配,中间有洗脱期。获取评分的研究人员保持盲态。参与者确定首选溶液、溶液是否舒缓以及哪种溶液引起的不适最大。参与者使用单独的视觉模拟量表评分对冲洗疼痛进行评级。

结果

38名患者纳入本研究。明显更多的人更喜欢温热溶液而非室温溶液(差异为34%;95%置信区间为5.7 - 63)。配对数据的Wilcoxon符号秩检验显示无顺序效应(P = 0.49),根据视觉模拟量表测量的疼痛也无差异(P = 0.082)。

结论

对于线性裂伤患者,温热盐水作为伤口冲洗液比室温盐水更舒适、更舒缓。

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