Ahmed Mohamed S Mohammed, Mori Atsunori
Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama 226-8503, Japan.
Org Lett. 2003 Aug 21;5(17):3057-60. doi: 10.1021/ol035007a.
[reaction: see text] Carbonylative coupling of phenylethyne with 4-methoxy-1-iodobenzene in the presence of 1 mol % PdCl(2)(PPh(3))(2), 2 equiv of 0.5 M aqueous ammonia, and CO (1 atm) gives the corresponding alpha,beta-alkynyl ketone in 72% isolated yield after stirring at room temperature for 41 h, while noncarbonylative coupling product is not obtained.
[反应：见正文] 在1 mol% PdCl₂(PPh₃)₂、2当量的0.5 M氨水和CO（1个大气压）存在下，苯乙炔与4-甲氧基-1-碘苯进行羰基化偶联反应，在室温下搅拌41小时后，以72%的分离产率得到相应的α,β-炔基酮，而未得到非羰基化偶联产物。
