Grier David G
Department of Physics, James Franck Institute and Institute for Biophysical Dynamics, The University of Chicago, 5640 S. Ellis Avenue, Chicago, IL 60637, USA.
Nature. 2003 Aug 14;424(6950):810-6. doi: 10.1038/nature01935.
Optical tweezers use the forces exerted by a strongly focused beam of light to trap and move objects ranging in size from tens of nanometres to tens of micrometres. Since their introduction in 1986, the optical tweezer has become an important tool for research in the fields of biology, physical chemistry and soft condensed matter physics. Recent advances promise to take optical tweezers out of the laboratory and into the mainstream of manufacturing and diagnostics; they may even become consumer products. The next generation of single-beam optical traps offers revolutionary new opportunities for fundamental and applied research.
光镊利用强聚焦光束施加的力来捕获和移动尺寸从几十纳米到几十微米不等的物体。自1986年问世以来,光镊已成为生物学、物理化学和软凝聚态物理领域研究的重要工具。最近的进展有望使光镊走出实验室,进入制造和诊断的主流领域;它们甚至可能成为消费品。新一代单光束光阱为基础研究和应用研究提供了革命性的新机遇。