Buitenhuis A J, Rodenburg T B, van Hierden Y M, Siwek M, Cornelissen S J B, Nieuwland M G B, Crooijmans R P M A, Groenen M A M, Koene P, Korte S M, Bovenhuis H, van der Poel J J
Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, Marijkeweg 40, NL-6709 PG Wageningen, The Netherlands.
Poult Sci. 2003 Aug;82(8):1215-22. doi: 10.1093/ps/82.8.1215.
In the European Union, legislation concerning animal housing is becoming stricter because of animal welfare concerns. Feather pecking (FP) in large group housing systems is a major problem. It has been suggested that corticosterone (CORT) response to manual restraint as a measure for stress is associated with FP behavior. The aim of the current study was to identify QTL involved in FP behavior and stress response in laying hens. An F2 population of 630 hens was established from a cross between two commercial lines of laying hens differing in their propensity to feather peck. The behavioral traits, measured at 6 and 30 wk of age, were gentle FP, severe FP, and aggressive pecking. Toe pecking was measured at 30 wk of age and CORT response to manual restraint was measured at 32 wk. All animals were genotyped for 180 microsatellite markers. A QTL analysis was performed using a regression interval mapping method. At 6 wk of age, a suggestive QTL on GGA10 was detected for gentle FP. At 30 wk of age, suggestive QTL were detected on GGA1 and GGA2 for gentle FP. A significant QTL was detected on GGA2 for severe FP. At 32 wk of age, a suggestive QTL was detected on GGA18 for CORT response to manual restraint. In addition, a suggestive QTL was detected on GGA5 with possible maternal parent-of-origin effect for CORT response.
在欧盟，由于对动物福利的关注，有关动物饲养的法规正变得更加严格。在大型群体饲养系统中，啄羽行为（FP）是一个主要问题。有人提出，将皮质酮（CORT）对手动约束的反应作为应激指标与啄羽行为有关。本研究的目的是鉴定蛋鸡中参与啄羽行为和应激反应的数量性状基因座（QTL）。从两个在啄羽倾向方面存在差异的商业蛋鸡品系杂交后代中建立了一个由630只母鸡组成的F2群体。在6周龄和30周龄时测量的行为性状包括轻度啄羽、重度啄羽和攻击性啄羽。在30周龄时测量趾部啄羽，在32周龄时测量CORT对手动约束的反应。所有动物均针对180个微卫星标记进行基因分型。使用回归区间作图法进行QTL分析。在6周龄时，在GGA10上检测到一个与轻度啄羽相关的暗示性QTL。在30周龄时，在GGA1和GGA2上检测到与轻度啄羽相关的暗示性QTL。在GGA2上检测到一个与重度啄羽相关的显著QTL。在32周龄时，在GGA18上检测到一个与CORT对手动约束的反应相关的暗示性QTL。此外，在GGA5上检测到一个可能具有母本起源效应的与CORT反应相关的暗示性QTL。
