Kohn B, Weingart C, Giger U
Clinic for Small Animals, Free University of Berlin, D-14163 Berlin, Germany.
J Feline Med Surg. 2003 Oct;5(5):295-304. doi: 10.1016/S1098-612X(03)00022-6.
Clinical features were evaluated in seven adult cats (six males, one female) with haemorrhage and presumptive anticoagulant rodenticide intoxication. Haemorrhage appeared as thoracic haemorrhage, otic bleeding, haematoma, melena, haematochezia, and petechiation. The most common other presenting signs were lethargy, anorexia, and tachypnoea or dyspnoea. Six cats were anaemic, four cats were mildly thrombocytopenic (58000-161000/ microL), and three had slightly decreased plasma protein or albumin values. The prothrombin time (30.3->100 s, reference range: 16.5-27.5 s) and activated partial thromboplastin time values (32.6->100 s; reference range: 14-25 s) were markedly prolonged in all cats. All cats received vitamin K(1)subcutaneously or orally (3.7-5 mg/kg body weight initially) and depending on severity of signs five cats were transfused with fresh whole blood. Plasma coagulation times improved in all cats and returned to normal in 1-5 days. Rodenticide poisons represent an important but relatively rare cause of haemorrhage in cats and can be effectively treated.
对7只患有出血且疑似抗凝血灭鼠剂中毒的成年猫（6只雄性，1只雌性）的临床特征进行了评估。出血表现为胸腔出血、耳部出血、血肿、黑便、便血和瘀点。其他最常见的症状是嗜睡、厌食和呼吸急促或呼吸困难。6只猫贫血，4只猫轻度血小板减少（58000 - 161000/微升），3只猫血浆蛋白或白蛋白值略有下降。所有猫的凝血酶原时间（30.3 -> 100秒，参考范围：16.5 - 27.5秒）和活化部分凝血活酶时间值（32.6 -> 100秒；参考范围：14 - 25秒）均显著延长。所有猫均接受了维生素K1皮下或口服给药（初始剂量为3.7 - 5毫克/千克体重），根据症状严重程度，5只猫输注了新鲜全血。所有猫的血浆凝血时间均有所改善，并在1 - 5天内恢复正常。灭鼠剂中毒是猫出血的一个重要但相对罕见的原因，且可以得到有效治疗。
