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本文引用的文献

1
Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus.金黄色葡萄球菌自然群体中黏附素与毒素基因的毒性组合
Infect Immun. 2002 Sep;70(9):4987-96. doi: 10.1128/IAI.70.9.4987-4996.2002.
2
Staphylococcus aureus fibronectin binding proteins A and B possess a second fibronectin binding region that may have biological relevance to bone tissues.金黄色葡萄球菌纤连蛋白结合蛋白A和B拥有第二个纤连蛋白结合区域，该区域可能与骨组织具有生物学相关性。
Calcif Tissue Int. 2002 May;70(5):416-21. doi: 10.1007/s00223-001-2073-z. Epub 2002 Mar 27.
3
Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease.金黄色葡萄球菌遗传背景、毒力因子、agr 组（等位基因）与人类疾病之间的关系。
Infect Immun. 2002 Feb;70(2):631-41. doi: 10.1128/IAI.70.2.631-641.2002.
4
Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis.通过在乳酸乳球菌中表达重新评估金黄色葡萄球菌聚集因子和纤连蛋白结合蛋白的作用。
Infect Immun. 2001 Oct;69(10):6296-302. doi: 10.1128/IAI.69.10.6296-6302.2001.
5
Collagen and fibronectin binding in experimental staphylococcal osteomyelitis.实验性葡萄球菌骨髓炎中胶原蛋白和纤连蛋白的结合
Clin Orthop Relat Res. 2001 Jan(382):241-6. doi: 10.1097/00003086-200101000-00032.
6
egc, a highly prevalent operon of enterotoxin gene, forms a putative nursery of superantigens in Staphylococcus aureus.肠毒素基因的一个高度流行的操纵子egc，在金黄色葡萄球菌中形成了一个假定的超抗原温床。
J Immunol. 2001 Jan 1;166(1):669-77. doi: 10.4049/jimmunol.166.1.669.
7
The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds to fibrinogen.金黄色葡萄球菌的纤连蛋白结合MSCRAMM FnbpA是一种双功能蛋白，它也能与纤维蛋白原结合。
J Biol Chem. 2000 May 5;275(18):13863-71. doi: 10.1074/jbc.275.18.13863.
8
A bone sialoprotein-binding protein from Staphylococcus aureus: a member of the staphylococcal Sdr family.一种来自金黄色葡萄球菌的骨唾液酸蛋白结合蛋白：葡萄球菌Sdr家族的一员。
Biochem J. 2000 Feb 1;345 Pt 3(Pt 3):611-9.
9
Surface protein adhesins of Staphylococcus aureus.金黄色葡萄球菌的表面蛋白黏附素
Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.
10
A polymerase chain reaction (PCR) method for the identification of collagen adhesin gene (CNA) in Staphylococcus-induced prosthesis infections.一种用于鉴定葡萄球菌引起的假体感染中胶原黏附素基因（CNA）的聚合酶链反应（PCR）方法。
New Microbiol. 1998 Oct;21(4):359-63.

运用多重聚合酶链反应鉴定参与人类血源性感染的金黄色葡萄球菌黏附素。

Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections.

作者信息

Tristan Anne, Ying Liu, Bes Michele, Etienne Jerome, Vandenesch Francois, Lina Gerard

机构信息

Centre National de Référence des Staphylocoques, INSERM E0230, IFR62 Laennec, 69372 Lyon Cédex 08, France.

出版信息

J Clin Microbiol. 2003 Sep;41(9):4465-7. doi: 10.1128/JCM.41.9.4465-4467.2003.

DOI:10.1128/JCM.41.9.4465-4467.2003
PMID:12958296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC193818/
Abstract

We have developed a multiplex PCR procedure to determine the distribution of nine adhesin genes in Staphylococcus aureus isolates. Only genes encoding bone sialoprotein binding protein and fibronectin binding protein B were significantly associated with hematogenous osteomyelitis/arthritis and native-valve endocarditis, respectively, suggesting their involvement in hematogenous tissue infections.

摘要

我们开发了一种多重聚合酶链反应程序，以确定金黄色葡萄球菌分离株中9种粘附素基因的分布。仅编码骨唾液蛋白结合蛋白和纤连蛋白结合蛋白B的基因，分别与血源性骨髓炎/关节炎和天然瓣膜心内膜炎显著相关，这表明它们参与了血源性组织感染。