Rafael Míriam Silva, Tadei Wanderli Pedro, Recco-Pimentel Shirlei Maria
Coordena o de Pesquisas em Ciências da Saúde, Instituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.
Mem Inst Oswaldo Cruz. 2003 Jul;98(5):629-35. doi: 10.1590/s0074-02762003000500008. Epub 2003 Sep 8.
Fluorescence in situ hybridization of Anopheles darlingi and A. nuneztovari demonstrated nucleolar organizer region activity at the end of the fourth larval instar, when the nucleolar organizer regions underwent gradual condensation. The heteromorphic sex chromosomes showed intraindividual size variation in the rDNA blocks located in the pericentromeric region and this coincided with the location of constitutive heterochromatin (C-banding).
对达林按蚊和努涅斯按蚊进行的荧光原位杂交显示,在第四龄幼虫末期,核仁组织区发生逐渐浓缩时,核仁组织区具有活性。异形性染色体在位于着丝粒周围区域的核糖体DNA(rDNA)区段表现出个体内大小差异,这与组成型异染色质(C带)的位置一致。