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外科病理科中标本固定的评估

Assessment of specimen fixation in a surgical pathology service.

作者信息

Start R D, Cross S S, Smith J H

机构信息

Department of Histopathology, Northern General Hospital, Sheffield.

出版信息

J Clin Pathol. 1992 Jun;45(6):546-7. doi: 10.1136/jcp.45.6.546.

DOI:10.1136/jcp.45.6.546
PMID:1306049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC495239/
Abstract

The quality of specimen fixation was examined within a routine diagnostic histopathology service. For each specimen the adequacy of fixation was assessed and the transit time between operating theatre and the laboratory was measured. Preliminary fixation was found to be inadequate in 25% of specimens and some form of manipulation to assist fixation was required in 36% of specimens. The mean transit time was 22 (SD 10.7) hours. Specimen fixation and transport are additional factors to consider in quality assurance of histopathology.

摘要

在常规诊断组织病理学服务中检查了标本固定的质量。对于每个标本,评估了固定的充分性,并测量了从手术室到实验室的转运时间。发现25%的标本初步固定不充分,36%的标本需要某种形式的操作来辅助固定。平均转运时间为22(标准差10.7)小时。标本固定和运输是组织病理学质量保证中需要考虑的额外因素。

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本文引用的文献

1
The effects of progressive formaldehyde fixation on the preservation of tissue antigens.渐进式甲醛固定对组织抗原保存的影响。
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Specimen transport audit.标本运输审核
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3
Does delay in fixation affect the number of mitotic figures in processed tissue?固定延迟是否会影响处理后组织中的有丝分裂象数量?
J Clin Pathol. 1990 Jul;43(7):597-9. doi: 10.1136/jcp.43.7.597.
4
Audit of turn-around times in a microbiology laboratory.微生物实验室周转时间审计。
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Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms.石蜡切片中增殖细胞核抗原(PCNA)的免疫定位:一种细胞增殖指标,在某些肿瘤中存在表达失调的证据。
J Pathol. 1990 Dec;162(4):285-94. doi: 10.1002/path.1711620403.
6
Is the grading of breast carcinomas affected by a delay in fixation?乳腺癌的分级会受到固定延迟的影响吗?
Virchows Arch A Pathol Anat Histopathol. 1991;419(6):475-7. doi: 10.1007/BF01650675.