Dunteman G H, Condelli W S, Fairbank J A
Research Triangle Institute, Research Triangle Park, NC 27709.
Hosp Community Psychiatry. 1992 Jun;43(6):608-11. doi: 10.1176/ps.43.6.608.
Findings from a large-scale national study of clients admitted to publicly funded drug treatment programs between 1979 and 1981 were used to determine whether cocaine use by current and former methadone patients could be predicted. The sample for this analysis comprised 526 daily or weekly heroin users admitted to 17 methadone maintenance programs. The study found that cocaine use by both current and former methadone patients showed an overall decline during the follow-up year; that patients who stopped using heroin after entering treatment were much more likely to quit using cocaine than were their heroin-using counterparts; and that the odds of initiating cocaine use after admission to a methadone program were much higher among patients who continued using heroin. These findings suggest that methadone programs may be able to reduce cocaine use among some patients by improving their effectiveness in reducing heroin use.
一项针对1979年至1981年间进入公共资助药物治疗项目的患者的大规模全国性研究结果，被用于确定当前和以前的美沙酮患者使用可卡因的情况是否可以被预测。该分析的样本包括526名每日或每周使用海洛因的患者，他们进入了17个美沙酮维持治疗项目。研究发现，当前和以前的美沙酮患者使用可卡因的情况在随访年度总体呈下降趋势；进入治疗后停止使用海洛因的患者比仍在使用海洛因的患者更有可能戒掉可卡因；并且在进入美沙酮项目后开始使用可卡因的几率在仍在使用海洛因的患者中要高得多。这些发现表明，美沙酮项目可能能够通过提高其减少海洛因使用的效果，来减少一些患者的可卡因使用。
