Magarò M, Mirone L, Altomonte L, Zoli A, Angelosante S
Divisione di Reumatologia, Università cattolica del Sacro Cuore, Roma, Italia.
Clin Rheumatol. 1992 Jun;11(2):231-4. doi: 10.1007/BF02207963.
The presence of anticardiolipin antibodies has recently been related to a clinical complex in which both central and peripheral neurologic damage is included. A series of 27 female patients affected by systemic lupus erythematosus (SLE) was tested for the presence of peripheral autonomic neuropathy and serum anticardiolipin antibody (ACA) levels were determined in each patient by ELISA. Peripheral autonomic impairment was detected in 40.7% of SLE patients and a large number (77.7%) of patients had elevated levels of ACA. No relationship was found between presence of ACA (both for IgG and IgM classes) and the autonomic neuropathy.
抗心磷脂抗体的存在最近与一种临床综合征相关，该综合征包括中枢和周围神经损伤。对一系列27名患有系统性红斑狼疮（SLE）的女性患者进行了外周自主神经病变检测，并通过酶联免疫吸附测定法（ELISA）测定了每位患者的血清抗心磷脂抗体（ACA）水平。在40.7%的SLE患者中检测到外周自主神经功能损害，并且大量患者（77.7%）的ACA水平升高。未发现ACA（IgG和IgM类）的存在与自主神经病变之间存在关联。
