Yirrell D L, Rogers C E, Blyth W A, Hill T J
Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, U.K.
Arch Virol. 1992;125(1-4):227-38. doi: 10.1007/BF01309640.
The primary replication of one strain of HSV was generally unaffected by the simultaneous inoculation of another strain either at the same site or at a different site within the same dermatome. Exceptions to this were the result of the generation of intertypic recombinants which were readily isolated only from sensory ganglia 5 and 6 days after inoculation with a mixture of HSV-1 and HSV-2 and from explant culture of the resultant latently infected ganglia. By restriction enzyme analysis the majority of the recombinant strains from primary infection were characterized as HSV 1; all those from latently infected ganglia were characterized as type 2.
