Modrow S, Höflacher B, Wolf H
Max von Pettenkofer-Institut, Munich, Federal Republic of Germany.
Arch Virol. 1992;127(1-4):379-86. doi: 10.1007/BF01309601.
Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8, P3HR1 and Raji cell lines. This protein could be shown to be membrane-associated, as predicted by previous computer analysis of the secondary structure and hydrophilicity pattern, and may be a member of EBV-induced membrane proteins in lytically infected cells.
使用针对源自开放阅读框BMRF2中编码的爱泼斯坦-巴尔病毒氨基酸序列潜在抗原区域的肽的单特异性兔血清，我们可以在化学诱导的B95-8、P3HR1和Raji细胞系中鉴定出一种53/55 kDa的蛋白质复合物。如先前对二级结构和亲水性模式的计算机分析所预测的那样，该蛋白质可被证明与膜相关，并且可能是裂解感染细胞中EBV诱导的膜蛋白的成员。
