von Heijne G
Nucleic Acids Res. 1986 Jun 11;14(11):4683-90. doi: 10.1093/nar/14.11.4683.
A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.
本文描述了一种用于识别分泌信号序列以及预测信号序列与成熟输出蛋白之间切割位点的新方法。对于原核生物和真核生物的蛋白质,预测准确率估计在75%至80%左右。