Brown F
United States Department of Agriculture, Greenport, New York 11944-0848.
Vaccine. 1992;10(14):1022-6. doi: 10.1016/0264-410x(92)90111-v.
The economically important foot-and-mouth disease has been successfully controlled in Western Europe by comprehensive immunization using killed vaccine. The author discusses the wisdom of abandoning this policy, and outlines research into alternative vaccines using recombinant DNA technology, in particular using synthetic peptides.
口蹄疫在经济上具有重要影响,通过使用灭活疫苗进行全面免疫接种,已在西欧成功得到控制。作者探讨了放弃这一政策是否明智,并概述了利用重组DNA技术,特别是利用合成肽研究替代疫苗的情况。