Ledwozyw A, Stolarczyk H, Siwek A
Department of Pathophysiology, Veterinary Faculty, Agricultural Academy, Lublin, Poland.
Acta Vet Hung. 1992;40(4):259-66.
The adherence of neutrophils from bronchopneumonic calves to nylon fibres and the influence of this adherence on O2- and H2O2 production were studied. Polymorphonuclear leukocytes from bronchopneumonic calves were found to produce much more superoxide anion and hydrogen peroxide than neutrophils from healthy animals. A higher production of these compounds was observed in granulocytes adhering to nylon fibres than in cells in suspension. It is suggested that oxygen radicals production induced by the contact of granulocytes with a solid surface plays a role in the destruction of endothelium in vivo.
研究了支气管肺炎犊牛中性粒细胞与尼龙纤维的黏附情况以及这种黏附对O2和H2O2产生的影响。发现支气管肺炎犊牛的多形核白细胞比健康动物的中性粒细胞产生更多的超氧阴离子和过氧化氢。与悬浮状态的细胞相比，黏附于尼龙纤维的粒细胞中这些化合物的产生量更高。提示粒细胞与固体表面接触诱导产生的氧自由基在体内内皮细胞破坏中起作用。
