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多形核白细胞在犊牛支气管肺炎发病机制中的作用。III. 血小板对粒细胞的激活作用。

The involvement of polymorphonuclear leukocytes in the pathogenesis of bronchopneumonia in calves. III. Granulocyte activation by platelets.

作者信息

Ledwozyw A, Stolarczyk H

机构信息

Department of Pathophysiology, Veterinary Faculty, Agricultural Academy, Lublin, Poland.

出版信息

Acta Vet Hung. 1991;39(3-4):197-201.

PMID:1664652
Abstract

The influence of platelets and platelet lysate on superoxide anion production and beta-glucuronidase release from neutrophils was investigated. Neither the suspension of unstimulated platelets from healthy calves nor its lysate had any influence on O2- production and enzyme release On the other hand, a great rise in superoxide anion production and beta-glucuronidase release was observed in the case of platelets from bronchopneumonic calves. It is suggested that platelets of bronchopneumonic calves can activate polymorphonuclear leukocytes, causing their degranulation and aggravating superoxide anion production.

摘要

研究了血小板和血小板裂解物对中性粒细胞超氧阴离子产生及β-葡萄糖醛酸酶释放的影响。来自健康小牛的未刺激血小板悬液及其裂解物均对O2-产生和酶释放无任何影响。另一方面,在支气管肺炎小牛的血小板中,观察到超氧阴离子产生和β-葡萄糖醛酸酶释放大幅增加。提示支气管肺炎小牛的血小板可激活多形核白细胞,导致其脱颗粒并加重超氧阴离子的产生。

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