Ledwozyw A, Stolarczyk H
Department of Pathophysiology, Veterinary Faculty, Agricultural Academy, Lublin, Poland.
Acta Vet Hung. 1991;39(3-4):203-13.
Stable oxidant and hypochlorous acid production in neutrophils of bronchopneumonic calves was investigated. The production of these compounds was much more intense in neutrophils of diseased calves than in the control cells. The production of stable oxidants and hypochlorous acid was restrained by free radical scavengers. Functional response of neutrophils was inhibited by cyclooxygenase products and stimulated by lipoxygenase products of the arachidonic acid cascade. Superoxide anion production is not connected with the degranulation process (beta-glucuronidase release), and the two events are under different control mechanisms.
对支气管肺炎犊牛中性粒细胞中稳定氧化剂和次氯酸的产生进行了研究。患病犊牛中性粒细胞中这些化合物的产生比对照细胞强烈得多。自由基清除剂可抑制稳定氧化剂和次氯酸的产生。中性粒细胞的功能反应受到环氧化酶产物的抑制，并受到花生四烯酸级联反应中脂氧化酶产物的刺激。超氧阴离子的产生与脱颗粒过程（β-葡萄糖醛酸酶释放）无关，这两个事件受不同的控制机制调节。
