Rutty G N, Richman P I, Laing J H
Department of Histopathology, Mount Vernon Hospital, Northwood, Middlesex, UK.
Histopathology. 1992 Nov;21(5):465-8. doi: 10.1111/j.1365-2559.1992.tb00432.x.
We have examined proliferative activity in a series of pilar and trichilemmal cysts using an antibody to proliferating cell nuclear antigen. In benign lesions proliferative activity was confined to the basal layers of the squamous epithelium. Lesions showing malignant change showed increased proliferative activity and were not confined to the basal layer. These findings were correlated with studies on DNA content using flow cytometry.
我们使用增殖细胞核抗原抗体检测了一系列毛囊囊肿和外毛根鞘囊肿中的增殖活性。在良性病变中，增殖活性局限于鳞状上皮的基底层。显示恶变的病变增殖活性增加，且不限于基底层。这些发现与使用流式细胞术对DNA含量的研究相关。
