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对墨西哥农村地区接触农药人群的姐妹染色单体交换分析。

Sister-chromatid exchange analysis in a rural population of Mexico exposed to pesticides.

作者信息

Gómez-Arroyo S, Noriega-Aldana N, Osorio A, Galicia F, Ling S, Villalobos-Pietrini R

机构信息

Laboratorio de Genética, Universidad Autónoma de Tlaxcala, Mexico.

出版信息

Mutat Res. 1992 Mar;281(3):173-9. doi: 10.1016/0165-7992(92)90005-3.

DOI:10.1016/0165-7992(92)90005-3
PMID:1371839
Abstract

Cytogenetic damage was evaluated by means of the analysis of sister-chromatid exchange (SCE) in a rural population of Tlaxcala, Mexico, in occupational contact with pesticides. We studied 170 men, 94 exposed and 76 not exposed. It was shown that SCE followed a normal distribution and Student's t test did not present differences between the two groups (P = 0.4). The frequency of SCE was not correlated with the duration of exposure of the rural workers (r = -0.06), the multiple covariance analysis applied to the data of duration of exposure, tobacco intake and alcohol ingestion demonstrated a lack of statistical significance. In the exposed people we observed no symptoms provoked by these compounds.

摘要

通过对墨西哥特拉斯卡拉州一个与农药有职业接触的农村人群的姐妹染色单体交换(SCE)分析来评估细胞遗传学损伤。我们研究了170名男性,其中94名接触农药,76名未接触。结果表明,SCE呈正态分布,两组之间的学生t检验无差异(P = 0.4)。SCE频率与农村工人的接触时间无关(r = -0.06),对接触时间、烟草摄入量和酒精摄入量数据进行的多元协方差分析显示无统计学意义。在接触人群中,我们未观察到这些化合物引发的症状。

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