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接触杀虫剂的农业工人淋巴细胞中的姐妹染色单体交换

Sister chromatid exchange in lymphocytes of agricultural workers exposed to pesticides.

作者信息

Carbonell E, Puig M, Xamena N, Creus A, Marcos R

机构信息

Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.

出版信息

Mutagenesis. 1990 Jul;5(4):403-5. doi: 10.1093/mutage/5.4.403.

DOI:10.1093/mutage/5.4.403
PMID:2398822
Abstract

Sister chromatid exchange (SCE) was studied in the lymphocytes of 27 agricultural workers occupationally exposed to several pesticides and 28 matched controls from el Maresme, an agricultural area near Barcelona. Comparison between both groups with the t-test did not reveal significant differences. These negative findings suggest that, possibly, the exposure level is too low to increase SCE in human lymphocytes in vivo. Our results indicate that smokers, both the workers and the controls, had a higher SCE frequency than non-smokers, in agreement with previous data reported by different authors.

摘要

对27名职业性接触多种农药的农业工人以及来自巴塞罗那附近农业区马雷斯梅的28名配对对照者的淋巴细胞进行了姐妹染色单体交换(SCE)研究。两组之间的t检验比较未显示出显著差异。这些阴性结果表明,接触水平可能过低,无法在体内增加人类淋巴细胞中的SCE。我们的结果表明,无论是工人还是对照者中的吸烟者,其SCE频率均高于非吸烟者,这与不同作者先前报道的数据一致。

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