DRESSER D W
Immunology. 1960 Oct;3(4):289-95.
The elimination of I-labelled BGG from the circulation of the mouse has been used as a measure of the immune response to BGG. It has been shown that intravenous injection of BGG solution alone is an unreliable method of immunization. Successful immunization was obtained after subcutaneous injection of Freund's adjuvant containing BGG. BSA and HSA have short biological half-lives in adult CBA mice. They are therefore unsuitable for use with the antigen elimination technique.
从小鼠循环系统中清除 I 标记的牛血清球蛋白(BGG)已被用作衡量对 BGG 免疫反应的一种方法。已表明单独静脉注射 BGG 溶液是一种不可靠的免疫方法。在皮下注射含 BGG 的弗氏佐剂后获得了成功的免疫。牛血清白蛋白(BSA)和人血清白蛋白(HSA)在成年 CBA 小鼠体内具有较短的生物半衰期。因此,它们不适用于抗原清除技术。