川崎病中的单核细胞亚群与冠状动脉病变
Mononuclear cell subsets and coronary artery lesions in Kawasaki disease.
作者信息
Furukawa S, Matsubara T, Yabuta K
机构信息
Department of Paediatrics, Juntendo University School of Medicine, Tokyo, Japan.
出版信息
Arch Dis Child. 1992 Jun;67(6):706-8. doi: 10.1136/adc.67.6.706.
Abstract
The peripheral blood mononuclear cell subsets in patients with Kawasaki disease and coronary artery lesions were investigated. Of the 106 patients 14 had lesions. Patients with Kawasaki disease and coronary artery lesions were found to have increased counts of CD14+ macrophages/monocytes compared with those of patients with Kawasaki disease without lesions. The absolute counts of CD14+ macrophages/monocytes form an important parameter to determine the severity of vascular damage during acute Kawasaki disease.
摘要
对川崎病患者及有冠状动脉病变患者的外周血单个核细胞亚群进行了研究。106例患者中，14例有病变。发现川崎病合并冠状动脉病变的患者与无病变的川崎病患者相比，CD14 +巨噬细胞/单核细胞计数增加。CD14 +巨噬细胞/单核细胞的绝对计数是确定急性川崎病期间血管损伤严重程度的一个重要参数。
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本文引用的文献
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Expression of Fc epsilon R2/CD23 on peripheral blood macrophages/monocytes in Kawasaki disease.川崎病患者外周血巨噬细胞/单核细胞上FcεR2/CD23的表达
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