Coats A J, Murphy C, Conway J, Sleight P
Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford.
Br Heart J. 1992 Aug;68(2):223-9. doi: 10.1136/hrt.68.8.223.
To develop and validate a high temporal resolution spectral analysis system for Doppler measurements of blood velocity in the ascending aorta.
An observational laboratory and clinical study comparing Doppler velocity-based measurements with fluid collection, electromagnetic flow catheters and probes, and thermodilution.
Tertiary referral cardiology unit and cardiac catheter laboratory.
Patients undergoing routine cardiac catheterisation for ischaemic heart disease, cardiac failure, and primary pulmonary hypertension.
There was good agreement between Doppler-derived and electromagnetic cuff or catheter measurements of velocity in an experimental flow rig (SD of differences 4.75% for velocity integral) and in the patients (SD of differences 4% for velocity integral). There was also reasonably good agreement between simultaneous Doppler-derived and thermodilution-estimated cardiac output measurements in patients undergoing cardiac catheterisation (SD of differences 12.6%).
This new method of high temporal resolution spectral analysis improves the resolution of rapidly changing blood velocities and may improve the ability to describe blood velocity patterns in the ascending aorta.
开发并验证一种用于测量升主动脉血流速度的高时间分辨率频谱分析系统。
一项观察性实验室及临床研究,将基于多普勒速度的测量结果与液体收集、电磁血流导管及探头以及热稀释法进行比较。
三级转诊心脏病科及心导管实验室。
因缺血性心脏病、心力衰竭及原发性肺动脉高压接受常规心导管检查的患者。
在实验性血流装置中,多普勒衍生测量值与电磁袖带或导管测量的速度之间具有良好的一致性(速度积分差异的标准差为4.75%),在患者中也是如此(速度积分差异的标准差为4%)。在接受心导管检查的患者中,同时进行的多普勒衍生测量值与热稀释法估计的心输出量测量值之间也具有合理的良好一致性(差异的标准差为12.6%)。
这种新的高时间分辨率频谱分析方法提高了对快速变化血流速度的分辨率,并可能提高描述升主动脉血流速度模式的能力。