Chandraratna P A, Nanna M, McKay C, Nimalasuriya A, Swinney R, Elkayam U, Rahimtoola S H
Am J Cardiol. 1984 Jan 1;53(1):234-7. doi: 10.1016/0002-9149(84)90718-5.
To evaluate the accuracy of a new, portable, continuous-wave Doppler computer (Ultracom) in measuring cardiac output (CO), simultaneous thermodilution CO and Doppler CO were measured in triplicate in 39 selected patients. Technically adequate Doppler CO studies were obtained in 36 patients. Aortic root diameter was measured by echocardiography and the cross-sectional area was calculated. A continuous-wave Doppler transducer was placed in the suprasternal notch, directed toward the ascending aorta and angled until the maximal velocity signal was achieved. The systolic velocity integral was computed using fast Fourier transform technique. The Doppler CO was computed from the equation: CO = aortic cross-sectional area X systolic velocity integral X heart rate. Interobserver and intraobserver variability studies were also performed. CO measured by thermodilution ranged from 1.86 to 10.1 liters/min (mean 5.26 +/- 1.91 [+/- standard deviation]) and CO by the Doppler method ranged from 1.63 to 10.9 liters/min (mean 5.32 +/- 1.83). The correlation coefficient was 0.97 (p less than 0.001) and standard error of the estimate was 0.42. The regression equation showed that Doppler CO = 0.408 + 0.93 X thermodilution CO. The correlation in 29 volunteers for interobserver variability was 0.98 (p less than 0.001) and in 18 volunteers for intraobserver variability was 0.97 (p less than 0.001). Thus, CO can be determined accurately in many patients using this Doppler technique by trained and experienced persons; intra- and interobserver variability is small.
为评估一种新型便携式连续波多普勒计算机(Ultracom)测量心输出量(CO)的准确性,对39例选定患者同时进行了三次热稀释法心输出量和多普勒法心输出量测量。36例患者获得了技术上足够的多普勒心输出量研究数据。通过超声心动图测量主动脉根部直径并计算横截面积。将连续波多普勒换能器置于胸骨上切迹,朝向升主动脉并调整角度直至获得最大速度信号。使用快速傅里叶变换技术计算收缩期速度积分。根据公式计算多普勒心输出量:心输出量=主动脉横截面积×收缩期速度积分×心率。还进行了观察者间和观察者内变异性研究。热稀释法测量的心输出量范围为1.86至10.1升/分钟(平均5.26±1.91[±标准差]),多普勒法测量的心输出量范围为1.63至10.9升/分钟(平均5.32±1.83)。相关系数为0.97(p<0.001),估计标准误差为0.42。回归方程显示多普勒心输出量=0.408+0.93×热稀释法心输出量。29名志愿者观察者间变异性的相关性为0.98(p<0.001),18名志愿者观察者内变异性的相关性为0.97(p<0.001)。因此,经过培训且经验丰富的人员使用这种多普勒技术可在许多患者中准确测定心输出量;观察者内和观察者间变异性较小。