Birkhead J S
Department of Medicine, Northampton General Hospital.
BMJ. 1992 Aug 22;305(6851):445-8. doi: 10.1136/bmj.305.6851.445.
To measure the delays between onset of symptoms and admission to hospital and provision of thrombolysis in patients with possible acute myocardial infarction.
Observational study of patients admitted with suspected myocardial infarction during six months.
Six district general hospitals in Britain.
1934 patients admitted with suspected myocardial infarction.
Route of admission to hospital and time to admission and thrombolysis.
Patients who made emergency calls did so sooner after onset of symptoms than those who called their doctor (median time 40 (95% confidence interval 30 to 52) minutes v 70 (60 to 90) minutes). General practitioners took a median of 20 (20 to 25) minutes to visit patients, rising to 30 (20 to 30) minutes during 0800-1200. The median time from call to arrival in hospital was 41 (38 to 47) minutes for patients who called an ambulance from home and 90 (90 to 94) minutes for those who contacted their doctor. The median time from arrival at hospital to thrombolysis was 80 (75 to 85) minutes for patients who were treated in the cardiac care unit and 31 (25 to 35) minutes for those treated in the accident and emergency department.
The time from onset of symptoms to thrombolysis could be reduced substantially by more effective use of emergency services and faster provision of thrombolysis in accident and emergency departments.
测量疑似急性心肌梗死患者症状发作至入院以及接受溶栓治疗之间的延迟时间。
对六个月内收治的疑似心肌梗死患者进行观察性研究。
英国的六家地区综合医院。
1934例疑似心肌梗死患者。
入院途径以及入院和溶栓时间。
拨打急救电话的患者在症状发作后比拨打医生电话的患者更早拨打电话(中位时间40(95%置信区间30至52)分钟对70(60至90)分钟)。全科医生出诊的中位时间为20(20至25)分钟,在08:00 - 12:00期间升至30(20至30)分钟。从家中拨打救护车的患者从打电话到入院的中位时间为41(38至47)分钟,联系医生的患者为90(90至94)分钟。在心脏监护病房接受治疗的患者从入院到溶栓的中位时间为80(75至85)分钟,在急诊科接受治疗的患者为31(25至35)分钟。
通过更有效地利用急救服务以及在急诊科更快地提供溶栓治疗,可大幅缩短从症状发作到溶栓的时间。