Wood C, Ewen A, Goresky G, Sheppard S
Department of Anaesthesia, Alberta Children's Hospital, University of Calgary.
Can J Anaesth. 1992 Sep;39(7):682-6. doi: 10.1007/BF03008230.
This study was undertaken to quantify the exposure of operating room staff to nitrous oxide during routine paediatric otolaryngeal surgery and to determine the influence of the method of induction of anaesthesia on this exposure. The nitrous oxide exposure of the anaesthetist, the surgeon and the circulating nurse were measured, using body-worn passive atmospheric samplers, during twelve routine paediatric otolaryngeal surgical lists. During six of the lists an inhalational technique, with nitrous oxide, oxygen and halothane, was used for the induction of anaesthesia. During the other six lists anaesthesia was induced using intravenous thiopentone. In all cases, anaesthesia was maintained using nitrous oxide, oxygen and halothane. Regardless of the induction technique used, the mean nitrous oxide exposures of the anaesthetist, the surgeon and the nurse all exceeded the maximum level of 25 ppm.hr-1 recommended by the United States National Institute for Occupational Safety and Health (NIOSH). The use of an intravenous technique for the induction of anaesthesia reduced the nitrous oxide exposure of the anaesthetist and the circulating nurse. This suggests that, although the use of an intravenous induction may reduce exposure to nitrous oxide, the NIOSH recommendations for maximum exposure of operating room personnel to nitrous oxide are currently unattainable in practice.
本研究旨在量化常规小儿耳鼻喉手术期间手术室工作人员对一氧化二氮的暴露量,并确定麻醉诱导方法对这种暴露的影响。在十二例常规小儿耳鼻喉手术中,使用可穿戴式被动大气采样器测量麻醉师、外科医生和巡回护士的一氧化二氮暴露量。在其中六例手术中,采用吸入技术,使用一氧化二氮、氧气和氟烷进行麻醉诱导。在另外六例手术中,使用静脉注射硫喷妥钠诱导麻醉。在所有情况下,均使用一氧化二氮、氧气和氟烷维持麻醉。无论采用何种诱导技术,麻醉师、外科医生和护士的平均一氧化二氮暴露量均超过了美国国家职业安全与健康研究所(NIOSH)推荐的25 ppm·hr-1的最高水平。使用静脉注射技术诱导麻醉可降低麻醉师和巡回护士的一氧化二氮暴露量。这表明,尽管使用静脉诱导可能会减少一氧化二氮的暴露,但目前在实际操作中,NIOSH关于手术室人员一氧化二氮最大暴露量的建议是无法实现的。