Chana T, Han X, Dagg B, Lawrie A S, Gooding R P, Eustace D L, Fletcher C D, Heyderman E
Department of Histopathology, UMDS, St Thomas Hospital, London, U.K.
J Pathol. 1992 Aug;167(4):391-7. doi: 10.1002/path.1711670408.
The murine monoclonal IgG1 kappa antibody TDM35 was raised against the cervical carcinoma cell line XH1. The antibody recognizes 18.5-66 kDa NCA-like glycoproteins and immunostains a variety of formalin-fixed, paraffin-embedded normal, benign, and malignant tissues. It is of value in the diagnosis of carcinoma of the exocrine pancreas and it identifies foci of squamous and glandular differentiation in other tumours. TDM35 should form a useful addition to a panel of antibodies for the evaluation of epithelial lesions.
鼠单克隆IgG1 κ抗体TDM35是针对宫颈癌细胞系XH1产生的。该抗体识别18.5 - 66 kDa的NCA样糖蛋白，并对多种福尔马林固定、石蜡包埋的正常、良性和恶性组织进行免疫染色。它在胰腺外分泌癌的诊断中具有价值，并且能识别其他肿瘤中的鳞状和腺性分化灶。TDM35应成为用于评估上皮性病变的一组抗体中的有用补充。
