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儿科流行病学中的病例对照研究:父母替代者以及不准确和选择性回忆的潜在陷阱。

Case-control studies in pediatric epidemiology: parent surrogates and potential pitfalls of inaccurate and selective recall.

作者信息

Pastides H, Goldberg R J

机构信息

Department of Biostatistics and Epidemiology, University of Massachusetts School of Public Health, Amherst.

出版信息

Soz Praventivmed. 1992;37(1):22-6. doi: 10.1007/BF01369098.

DOI:10.1007/BF01369098
PMID:1414002
Abstract

The case-control study is quite popular as a study design for exploring associations between risk factors and disease in pediatric epidemiology. Since data concerning exposures to the child are often collected through interviews with parents or other surrogates, researchers should be aware of the opportunities for bias due to inaccurate or incomplete recall. Methods which exist for the control of this problem are presented. These include: the selection of control groups with childhood conditions of similar etiologic uncertainty as the disease being studied; collecting exposure data from both parents; collection of data from children where possible; diligent interviewer training; reviewing clinical records; and use of validity scales. Strengths and weaknesses of these strategies are discussed.

摘要

病例对照研究作为一种探索儿科流行病学中危险因素与疾病之间关联的研究设计非常受欢迎。由于有关儿童暴露情况的数据通常是通过对父母或其他替代者的访谈收集的,研究人员应意识到因回忆不准确或不完整而导致偏差的可能性。本文介绍了控制这一问题的现有方法。这些方法包括:选择患有病因不确定性与所研究疾病相似的儿童疾病作为对照组;从父母双方收集暴露数据;尽可能从儿童那里收集数据;对访谈者进行认真培训;查阅临床记录;以及使用效度量表。文中还讨论了这些策略的优缺点。

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