Gharagozloo N Z, Baker R H, Brubaker R F
Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905.
Am J Ophthalmol. 1992 Oct 15;114(4):473-8. doi: 10.1016/s0002-9394(14)71860-4.
Eighteen untreated patients with unilateral exfoliation syndrome without glaucoma were studied with regard to differences in aqueous dynamics between the affected and unaffected fellow eyes. Additionally, both eyes of the patients with exfoliation were compared to the eyes of 18 age-matched and gender-matched control subjects. Intraocular pressure was significantly higher (13.9 +/- 3.0 mm Hg [mean +/- standard deviation]) in the affected compared with the unaffected eyes (12.2 +/- 2.5 mm Hg), but no difference in aqueous humor flow was detected when eyes in the three groups were compared (affected eyes, 2.40 +/- 0.60 microliter/min; unaffected eyes, 2.40 +/- 0.65 microliter/min; control eyes, 2.61 +/- 0.60 microliter/min). Anterior chamber volumes were significantly smaller in affected (122 +/- 37 microliters) and unaffected eyes (121 +/- 37 microliters) of the patients with exfoliation compared with the eyes of the control subjects (145 +/- 30 microliters). Apparent resistance was higher in the eyes with exfoliation (6.5 +/- 1.9 min mm Hg/microliters) compared with both unaffected (5.4 +/- 1.2 min mm Hg/microliters) and control groups (5.2 +/- 1.8 min mm Hg/microliters), although these differences were not statistically significant.
对18例未经治疗的单侧剥脱综合征且无青光眼的患者进行研究，以观察患眼与未患眼之间房水动力学的差异。此外，将剥脱综合征患者的双眼与18名年龄和性别匹配的对照受试者的眼睛进行比较。患眼的眼压（13.9±3.0 mmHg[平均值±标准差]）显著高于未患眼（12.2±2.5 mmHg），但比较三组眼睛时未检测到房水流量有差异（患眼，2.40±0.60微升/分钟；未患眼，2.40±0.65微升/分钟；对照眼，2.61±0.60微升/分钟）。与对照受试者的眼睛（145±30微升）相比，剥脱综合征患者患眼（122±37微升）和未患眼（121±37微升）的前房容积显著较小。与未患眼（5.4±1.2分钟mmHg/微升）和对照组（5.2±1.8分钟mmHg/微升）相比，剥脱综合征患者患眼的表观阻力较高（6.5±1.9分钟mmHg/微升），尽管这些差异无统计学意义。
