Johnell O, Gullberg B, Allander E, Kanis J A
Osteoporos Int. 1992 Nov;2(6):298-302. doi: 10.1007/BF01623186.
The objective of this study was to examine the apparent incidence of hip fracture from discharge rates in European countries. A request was sent to the Ministries of Health in all European countries, asking for the number of hip fracture patients by age and sex, between the years 1983 and 1985. Seventeen countries responded. As expected, hip fracture was most frequently found amongst the elderly, particularly women. The incidence of hip fracture rose exponentially with age in both sexes. It was higher in women than men and there was a three-fold range between countries in the female to male sex ratio. There was an eleven-fold range in apparent incidence amongst women and a seven-fold range amongst men between the various countries. The highest incidence was found in the northern part of Europe and the lowest in the Mediterranean area. There was a significant positive correlation between the age-standardized incidence rates reported in men from each country and that in women. There was a larger difference in incidence between countries than between sexes, which suggests important genetic or environmental factors in the causation of hip fracture. The extent to which this reflects imperfect capture of data is uncertain but will be important to determine in order to identify reasons for differences and to enable confident projections of the future magnitude of this disorder.
本研究的目的是通过欧洲国家的出院率来考察髋部骨折的表观发病率。向所有欧洲国家的卫生部发出请求，索要1983年至1985年间按年龄和性别划分的髋部骨折患者数量。17个国家作出了回应。正如预期的那样，髋部骨折在老年人中最为常见，尤其是女性。两性的髋部骨折发病率均随年龄呈指数上升。女性的发病率高于男性，各国女性与男性的性别比在3倍范围内。各国之间，女性的表观发病率相差11倍，男性相差7倍。发病率最高的是欧洲北部，最低的是地中海地区。各国报告的男性年龄标准化发病率与女性的发病率之间存在显著正相关。各国之间发病率的差异大于性别之间的差异，这表明在髋部骨折的病因中存在重要的遗传或环境因素。这在多大程度上反映了数据收集的不完整尚不确定，但为了确定差异的原因并能够对这种疾病未来的严重程度进行可靠预测，确定这一点很重要。
