Tijl J, Koornneef L, Eijpe A, Thomas L, Gonzalez D G, Veenhof C
Orbital Centre, University of Amsterdam, The Netherlands.
Graefes Arch Clin Exp Ophthalmol. 1992;230(6):527-30. doi: 10.1007/BF00181773.
In a retrospective study the records of 34 consecutive cases with tumors metastatic to the orbit were reviewed with special attention to the management and prognosis of these patients. The primary tumor site was the breast in 20 patients, prostate in 5, kidney in 2 and skin in 2. The remaining 5 patients had other primary tumour sites. The symptoms of orbital metastasis preceded the detection of the primary tumor in 8 cases (24%). Twenty patients died after a mean interval of 25 months following the diagnosis of the orbital metastasis. This study gives a summary of the clinical features of these patients. With improved methods of treatment it was possible to obtain a relief of orbital symptoms in 24 patients (71%). Although the life expectancy of these patients remains poor, treatment can result in symptomatic relief and in an improvement in the quality of life, which is the main goal in the management of these patients.
在一项回顾性研究中,对34例眼眶转移性肿瘤的连续病例记录进行了回顾,特别关注这些患者的治疗和预后。原发肿瘤部位在20例患者中为乳腺,5例为前列腺,2例为肾脏,2例为皮肤。其余5例患者有其他原发肿瘤部位。眼眶转移症状在8例(24%)患者中先于原发肿瘤被发现。20例患者在眼眶转移诊断后平均25个月死亡。本研究总结了这些患者的临床特征。随着治疗方法的改进,24例患者(71%)的眼眶症状得以缓解。尽管这些患者的预期寿命仍然较差,但治疗可导致症状缓解并改善生活质量,这是这些患者治疗的主要目标。