Wang M Q, Nicholson M E, Jones C S, Fitzhugh E C, Westerfield C R
Health and Human Performance Studies, University of Alabama, Tuscaloosa 35487.
Pharmacol Biochem Behav. 1992 Oct;43(2):641-3. doi: 10.1016/0091-3057(92)90205-t.
The present study compared alcohol pharmacokinetics associated with body weight, anthropometrically estimated total body water, and body mass index in men and women in two experimental sessions, single dose and double dose. All subjects were given the same amount of alcohol (2.3 and 4.6 oz. 86 proof vodka for single dose and double dose, respectively). Data analyses found a significant correlation between body mass index and peak blood alcohol concentration (BAC). Weight and total body water were not significantly correlated with peak BAC. The findings suggested that body mass index may be considered a better criterion than body weight for equating alcohol doses.
本研究在单剂量和双剂量两个实验阶段，比较了男性和女性中与体重、人体测量估算的总体水以及体重指数相关的酒精药代动力学。所有受试者均给予相同量的酒精（单剂量和双剂量分别为2.3盎司和4.6盎司86度伏特加）。数据分析发现体重指数与血中酒精浓度峰值（BAC）之间存在显著相关性。体重和总体水与BAC峰值无显著相关性。研究结果表明，在等量酒精剂量换算方面，体重指数可能比体重是更好的衡量标准。
