Kanoh T, Yago K, Iwata H, Tei K, Higashino T
Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan.
Urology. 1992 Nov;40(5):484-8. doi: 10.1016/0090-4295(92)90471-8.
A seventy-six-year-old woman with plasmacytoma presenting as a renal mass died three months after diagnosis. Bone surveys disclosed no lytic lesions. Gallium-67 scan showed an avid uptake of the radionuclide in the renal mass. Histologic and immunofluorescence studies of resected specimens demonstrated that the renal parenchyma was destroyed by sheets of immature plasma cells producing IgM-lambda and by massive deposits of amorphous, eosinophilic substance stained with anti-mu and anti-lambda antisera. The literature is reviewed. We believe this case is the first one of well-documented IgM-producing renal plasmacytoma.
一名76岁患有浆细胞瘤且表现为肾脏肿块的女性在诊断后三个月死亡。骨骼检查未发现溶骨性病变。镓-67扫描显示肾脏肿块对放射性核素有强烈摄取。对切除标本进行的组织学和免疫荧光研究表明，肾实质被产生IgM-λ的成片未成熟浆细胞以及被抗μ和抗λ抗血清染色的大量无定形嗜酸性物质沉积物破坏。对相关文献进行了综述。我们认为该病例是首例有充分记录的产生IgM的肾浆细胞瘤。
