Räihä I J, Impivaara O, Seppälä M, Sourander L B
Department of Geriatric Medicine, University of Turku, Finland.
J Am Geriatr Soc. 1992 Dec;40(12):1209-11. doi: 10.1111/j.1532-5415.1992.tb03643.x.
To study prevalence and characteristics of symptomatic gastroesophageal reflux disease in the elderly.
Survey by questionnaire of stratified random sample.
City of Turku, Finland.
Population-based random sample consisting of non-institutionalized subjects aged 65 years or over. A questionnaire was sent to 559 subjects. The response rate was 92%. Twenty-nine incompletely filled forms were rejected. Thus, the questionnaires from 487 subjects, representing 87% of the original number, constitute the basis for the study.
The questionnaire inquired about the following symptoms: heartburn, regurgitation, chest pain, dysphagia, dyspepsia, respiratory symptoms, vomiting, and belching.
The age-adjusted prevalence of daily symptoms suggestive of gastroesophageal reflux disease was 8% in men and 15% in women (P < 0.05). Fifty-four percent of men and 66% of women reported that they had symptoms at least once a month (P < 0.05). The prevalence of symptoms was roughly the same across age groups. The occurrence of chest pain, dyspepsia, vomiting, belching, dysphagia, chronic cough, hoarseness, and wheezing were associated with symptoms suggestive of gastroesophageal reflux disease.
Symptoms suggestive of gastroesophageal reflux disease are common in elderly subjects. Women suffer from these symptoms more frequently than men. Typical reflux symptoms are often associated with atypical complaints, such as abdominal symptoms, chest pain, or respiratory symptoms.
研究老年有症状的胃食管反流病的患病率及特征。
采用分层随机抽样问卷调查。
芬兰图尔库市。
以社区为基础的随机样本,由65岁及以上非住院患者组成。向559名受试者发放问卷,回复率为92%。29份填写不完整的问卷被剔除。因此,来自487名受试者的问卷(占原始数量的87%)构成了本研究的基础。
问卷询问了以下症状:烧心、反流、胸痛、吞咽困难、消化不良、呼吸道症状、呕吐和嗳气。
经年龄调整后,提示胃食管反流病的每日症状患病率男性为8%,女性为15%(P<0.05)。54%的男性和66%的女性报告他们至少每月出现一次症状(P<0.05)。各年龄组症状患病率大致相同。胸痛、消化不良、呕吐、嗳气、吞咽困难、慢性咳嗽、声音嘶哑和喘息的发生与提示胃食管反流病的症状相关。
提示胃食管反流病的症状在老年受试者中很常见。女性比男性更频繁地出现这些症状。典型的反流症状常与非典型症状相关,如腹部症状、胸痛或呼吸道症状。