Borrego J J, Castro D, Jimenez-Notario M, Luque A, Martinez-Manzanares E, Rodriguez-Avial C, Picazo J J
Departamento de Microbiología, Universidad de Málaga, Spain.
J Clin Microbiol. 1992 Dec;30(12):3058-64. doi: 10.1128/jcm.30.12.3058-3064.1992.
A comparative study of the phage types, antimicrobial susceptibility patterns, and plasmid profiles of 171 strains of Salmonella isolated from food, epidemic outbreaks, and water-contaminated environments as well as sporadic human isolates was carried out to determine the most adequate marker in epidemiological investigations. Typing based on the plasmid profiles appears to be the most effective method for grouping strains with the same serotype obtained from a single outbreak and from environmental sources. However, none of the three markers tested allow us total discrimination and identification of related strains from a common source for epidemiological tracing. Therefore, the combined use of the three methods is necessary for determining whether common source isolates are related.
对从食品、疫情暴发、水污染环境以及散发性人类分离株中分离出的171株沙门氏菌的噬菌体类型、抗菌药敏模式和质粒图谱进行了比较研究，以确定流行病学调查中最合适的标志物。基于质粒图谱的分型似乎是对从单一疫情暴发和环境来源获得的相同血清型菌株进行分组的最有效方法。然而，所测试的三种标志物均无法让我们完全区分和鉴定来自共同来源的相关菌株以进行流行病学追踪。因此，为了确定共同来源的分离株是否相关，有必要联合使用这三种方法。
