Johnson H L, Virk S P, Mayclin P, Barbieri T
US Department of Agriculture, Western Human Nutrition Research Center, Presidio of San Francisco, CA 94129.
J Am Coll Nutr. 1992 Oct;11(5):539-47. doi: 10.1080/07315724.1992.10718259.
Two biological impedance analyzers, a 50 kHz (RJL) and 20-100 kHz (BMA) instrument, and a total body electrical conductivity (TOBEC) instrument were used to estimate total body water (TBW), extracellular (ECF) and intracellular (ICF) fluid volumes by repeated measurements of 16 normal men (19-38 years old) to assess which, if any, would provide the best estimates. At 3-week intervals, TBW was determined by deuterium dilution, ECF by bromide dilution, ICF by difference (TBW-ECF) and lean body mass by density. Prediction equations were obtained by regression; predicted values for the body fluid volumes were calculated and the results were statistically evaluated. Both the TOBEC and the BMA provided rapid and reliable estimates for body fluid volumes with standard errors of the estimates of about 0.5-1.1 L for ECF, 1.0-1.8 L for TBW, and 1.0-1.3 L for ICF. Part of the error was attributable to standard tracer-dilution methods.
使用两台生物电阻抗分析仪，一台50 kHz（RJL）和一台20 - 100 kHz（BMA）仪器，以及一台全身电导率（TOBEC）仪器，通过对16名正常男性（19 - 38岁）进行重复测量来估计总体水（TBW）、细胞外液（ECF）和细胞内液（ICF）体积，以评估哪台仪器（如果有的话）能提供最佳估计值。每隔3周，通过氘稀释法测定TBW，通过溴化物稀释法测定ECF，通过差值法（TBW - ECF）测定ICF，并通过密度法测定去脂体重。通过回归获得预测方程；计算体液体积的预测值并对结果进行统计学评估。TOBEC和BMA都能快速且可靠地估计体液体积，ECF估计值的标准误差约为0.5 - 1.1 L，TBW为1.0 - 1.8 L，ICF为1.0 - 1.3 L。部分误差归因于标准示踪剂稀释法。
