迈向环状双肽核酸。
Towards a circular bis-peptide nucleic acid.
作者信息
Hudson R H E, Tse J
机构信息
Department of Chemistry, The University of Western Ontario, London, Ontario, Canada.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1023-7. doi: 10.1081/ncn-120022727.
PMID:14565335
Abstract
En route to a circular bis-PNA molecule, we have synthesized and characterized the DNA binding of several "clamp"-type bis-PNAs. In order to incorporate charge into a circular PNA, a new linker based on the achiral 2-aminoethylglycine has been used.
摘要
在通往环状双肽核酸（bis-PNA）分子的过程中，我们合成并表征了几种“钳夹”型双肽核酸与DNA的结合情况。为了将电荷引入环状肽核酸，一种基于非手性2-氨基乙基甘氨酸的新型连接子已被使用。
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