Lovejoy Jennifer C
Women's Nutrition Research Program, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA.
Prim Care. 2003 Jun;30(2):317-25. doi: 10.1016/s0095-4543(03)00012-5.
In summary, menopause tends to be associated with an increased risk of obesity and a shift to an abdominal fat distribution with associated increase in health risks. Changes in body composition at menopause may be caused by the decrease in circulating estrogen, and, for fat distribution shifts, the relative increase in the androgen-estrogen ratio is likely to be important. Clinicians need to be aware of the likelihood of weight gain during the perimenopausal and postmenopausal years because behavioral strategies for weight loss can be effectively used in this population. Weight loss or prevention of weight gain is likely to have significant health benefits for older women.
总之,更年期往往与肥胖风险增加以及脂肪分布向腹部转移相关,从而导致健康风险增加。更年期身体成分的变化可能是由循环雌激素减少引起的,而对于脂肪分布的改变,雄激素与雌激素比例的相对增加可能很重要。临床医生需要意识到围绝经期和绝经后体重增加的可能性,因为减肥的行为策略可以有效地应用于这一人群。减肥或预防体重增加可能对老年女性有显著的健康益处。