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希腊心血管危险因素的流行病学:阿提卡研究的目的、设计及基线特征

Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study.

作者信息

Pitsavos Christos, Panagiotakos Demosthenes B, Chrysohoou Christina, Stefanadis Christodoulos

机构信息

A' Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.

出版信息

BMC Public Health. 2003 Oct 20;3:32. doi: 10.1186/1471-2458-3-32.

Abstract

BACKGROUND

In an attempt to evaluate the levels of several cardiovascular risk factors in Greece we conducted a population-based health and nutrition survey, the "ATTICA study". In this work we present the design and the methodology of the study, as well as the status of various baseline characteristics of the participants.

METHODS

From May 2001 to December 2002 we randomly enrolled 1514 adult men and 1528 adult women, stratified by age--gender (census 2000), from the greater area of Athens. More than 300 demographic, lifestyle, behavioral, dietary, clinical and biochemical variables have been recorded.

RESULTS

Regarding the frequency of the classical cardiovascular risk factors we observed that 51% of men and 39% of women reported smokers (p < 0.05), 37% of men and 25% of women were defined as hypertensives (p < 0.05), 46% of men and 40% of women had total serum cholesterol levels above 200 mg/dl (p < 0.05) and 8% of men and 6% of women had history of diabetes mellitus. Moreover, 20% of men and 15% of women were obese (p < 0.05), while men were more physically active as compared to women (42% vs. 39%, p < 0.05). 19% of men and 38% of women had mild to severe depressive symptoms (p < 0.01). Finally, 72 men (5%) and 45 (3%) women reported history of coronary heart disease at entry evaluation.

CONCLUSIONS

The prevalence of the common cardiovascular risk factors in our population seems high. As a consequence a considerable proportion of Greek adults are at "high-risk" for future cardiovascular events.

摘要

背景

为了评估希腊人群中几种心血管危险因素的水平,我们开展了一项基于人群的健康与营养调查,即“阿提卡研究”。在本研究中,我们介绍了研究的设计与方法,以及参与者各种基线特征的情况。

方法

从2001年5月至2002年12月,我们从雅典大区按照年龄-性别(2000年人口普查数据)进行分层,随机招募了1514名成年男性和1528名成年女性。记录了300多个关于人口统计学、生活方式、行为、饮食、临床和生化方面的变量。

结果

关于经典心血管危险因素的发生率,我们观察到51%的男性和39%的女性报告为吸烟者(p<0.05),37%的男性和25%的女性被定义为高血压患者(p<0.05),46%的男性和40%的女性总血清胆固醇水平高于200mg/dl(p<0.05),8%的男性和6%的女性有糖尿病病史。此外,20%的男性和15%的女性肥胖(p<0.05),而男性比女性身体活动更多(42%对39%,p<0.05)。19%的男性和38%的女性有轻度至重度抑郁症状(p<0.01)。最后,在入组评估时,72名男性(5%)和45名(3%)女性报告有冠心病病史。

结论

我们人群中常见心血管危险因素的患病率似乎较高。因此,相当一部分希腊成年人未来发生心血管事件的风险“很高”。

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