Sims L D, Guan Y, Ellis T M, Liu K K, Dyrting K, Wong H, Kung N Y H, Shortridge K F, Peiris M
Agriculture, Fisheries, and Conservation Department, 303 Cheung Sha Wan Road, Kowloon, Hong Kong SAR, China.
Avian Dis. 2003;47(3 Suppl):1083-6. doi: 10.1637/0005-2086-47.s3.1083.
An outbreak of highly pathogenic avian influenza caused by multiple genotypes of H5N1 virus occurred in Hong Kong, commencing in January 2002. Infection in local chicken farms was preceded by the detection of virus in multiple retail markets and the main poultry wholesale market. The first case of this disease on a local farm was detected on February 1, 2002. By February 9, 2002, 15 farms were infected, and by late March a total of 22 infected farms had been identified. Three main clusters of infected farms were seen, suggesting multiple incursions of virus, and subsequent limited lateral spread to neighboring firms. Control of this disease has been effected through a combination of quarantine, tightening of biosecurity measures, and depopulation of infected and contact farms. About 950,000 birds have been destroyed. Vaccination using a killed H5 vaccine was introduced in April 2002 to farms in one zone where infection has persisted. None of the viruses isolated contained the internal genes found in the 1997 H5N1 virus.
2002年1月起，香港发生了由多种基因型H5N1病毒引起的高致病性禽流感疫情。在当地养鸡场出现感染之前，多个零售市场和主要家禽批发市场已检测到病毒。2002年2月1日，当地一个农场首次发现这种疾病的病例。到2002年2月9日，有15个农场受到感染，到3月下旬，共确认了22个受感染农场。发现了三个主要的受感染农场集群，表明病毒多次侵入，随后向邻近公司的横向传播有限。通过检疫、加强生物安全措施以及对受感染农场和接触农场进行扑杀相结合的方式对该疾病进行了控制。约95万只家禽被扑杀。2002年4月，在一个疫情持续的区域对农场采用灭活H5疫苗进行了接种。分离出的病毒均未含有1997年H5N1病毒中的内部基因。
