帕纳索斯荆芥油及分离出的荆芥内酯的化学成分与生物活性。
Chemical composition and biological activity of Nepeta parnassica oils and isolated nepetalactones.
作者信息
Gkinis Giorgos, Tzakou Olga, Iliopoulou Dimitra, Roussis Vassilios
机构信息
Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece.
出版信息
Z Naturforsch C J Biosci. 2003 Sep-Oct;58(9-10):681-6. doi: 10.1515/znc-2003-9-1015.
Essential oils of Nepeta parnassica, collected at different developmental stages, were analyzed by means of GC/MS. From the fifty-five identified constituents in samples A and B, representing 94.8% and 98.7% of the oils respectively, 4a(alpha),7alpha,7alpha(beta)-nepetalactone (22.0%), 1,8-cineole (21.1%), alpha-pinene (9.5%) and 4a(alpha),7,beta,7alpha(beta)-nepetalactone (7.9%) were the major components of sample A (vegetative stage), whereas in sample B (flowering stage) the main contributors were 1,8-cineole (34.6%), 4a(alpha),7alpha,7a(alpha)-nepetalactone (17.3%), alpha-pinene (11.4%) and 4a(alpha),7alpha,7alpha(beta)-nepetalactone (8.9%). The oils were tested on human health important insects such as the Pogonomyrmex sp. ants and the Culex pipiens molestus mosquitoes with promising results on insect repellency/toxicity.
对不同发育阶段采集的帕纳西山荆芥精油进行了气相色谱/质谱分析。在分别占精油94.8%和98.7%的样品A和样品B中鉴定出的55种成分里，4a（α），7α，7α（β）-荆芥内酯（22.0%）、1,8-桉叶素（21.1%）、α-蒎烯（9.5%）和4a（α），7，β，7α（β）-荆芥内酯（7.9%）是样品A（营养期）的主要成分，而在样品B（花期）中，主要成分是1,8-桉叶素（34.6%）、4a（α），7α，7a（α）-荆芥内酯（17.3%）、α-蒎烯（11.4%）和4a（α），7α，7α（β）-荆芥内酯（8.9%）。这些精油在对人类健康重要的昆虫如收获蚁属蚂蚁和骚扰库蚊上进行了测试，在驱虫/毒性方面取得了有前景的结果。
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