Cheng Ching-Yu, Hsu Wen-Ming, Liu Jorn-Hon, Tsai Su-Ying, Chou Pesus
Department of Ophthalmology, School of Medicine, Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan.
Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4630-8. doi: 10.1167/iovs.03-0169.
Few epidemiologic data are available on refractive status in elderly Asians. The purpose of the study was to determine prevalence and risk factors associated with refractive errors in a metropolitan elderly Chinese population in Taiwan.
A population-based survey was conducted in the Shihpai district of Taipei, Taiwan. A total of 2045 residents aged 65 years or more were randomly selected and invited to complete a comprehensive questionnaire and undertake a detailed ocular examination, including best corrected visual acuity and measurements of refractive error, using autorefraction. Of the subjects, 1361 (66.6%) participated in the ocular examination. Spherical equivalent (SE) was calculated in diopters (D), and data from right eyes were reported.
The age- and sex-adjusted prevalence rates were determined for myopia (SE<-0.5 D, 19.4%; SE<-1.0 D, 14.5%), high myopia (SE<-6.0 D, 2.4%), hyperopia (SE>+0.5 D, 59.0%; SE>+1.0 D, 44.2%), astigmatism (cylinder<-0.5 D, 74.0%; cylinder<-1.0 D, 45.3%), and anisometropia (SE difference between right and left eyes>0.5 D, 45.2%; SE difference>1.0 D, 21.8%). The prevalence of myopia, astigmatism, and anisometropia significantly increased with age (all P<0.01). The prevalence of hyperopia tended to decrease with age. There was no gender difference in prevalence rates in any type of refractive error, except that women had a higher rate of hyperopia (SE>+1.0 D) than men (P=0.004). Multivariate regression analysis showed that myopia was weakly associated with higher educational level. The severity of lens nuclear opacity was positively associated with the rates of myopia and negatively associated with the rates of hyperopia.
The prevalence of myopia in this elderly Chinese population is not much higher than in similarly aged elderly white populations, compared with a much greater difference in prevalence among younger Chinese versus white people. This suggests that changing environmental factors may account for the increased prevalence of myopia in younger cohorts of Chinese.
关于亚洲老年人屈光状态的流行病学数据较少。本研究旨在确定台湾大都市地区老年中国人群中屈光不正的患病率及相关危险因素。
在台湾台北市士林区进行了一项基于人群的调查。随机选取了2045名65岁及以上的居民,邀请他们完成一份综合问卷并进行详细的眼部检查,包括使用自动验光仪测量最佳矫正视力和屈光不正。其中,1361名受试者(66.6%)参与了眼部检查。以屈光度(D)计算等效球镜度(SE),并报告右眼的数据。
确定了年龄和性别调整后的近视患病率(SE<-0.5 D,19.4%;SE<-1.0 D,14.5%)、高度近视患病率(SE<-6.0 D,2.4%)、远视患病率(SE>+0.5 D,59.0%;SE>+1.0 D,44.2%)、散光患病率(柱镜<-0.5 D,74.0%;柱镜<-1.0 D,45.3%)和屈光参差患病率(右眼与左眼的SE差值>0.5 D,45.2%;SE差值>1.0 D,21.8%)。近视、散光和屈光参差的患病率随年龄显著增加(均P<0.01)。远视患病率随年龄呈下降趋势。除女性远视(SE>+1.0 D)患病率高于男性外(P=0.004),任何类型屈光不正的患病率均无性别差异。多因素回归分析显示,近视与较高的教育水平呈弱相关。晶状体核混浊的严重程度与近视患病率呈正相关,与远视患病率呈负相关。
与年轻中国人群和白种人群之间患病率的较大差异相比,该老年中国人群中的近视患病率并不比同龄老年白种人群高很多。这表明环境因素的变化可能是中国年轻人群近视患病率增加的原因。