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日本老年人群中的屈光不正:多治见研究

Refractive errors in an elderly Japanese population: the Tajimi study.

作者信息

Sawada Akira, Tomidokoro Atsuo, Araie Makoto, Iwase Aiko, Yamamoto Tetsuya

机构信息

Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan.

出版信息

Ophthalmology. 2008 Feb;115(2):363-370.e3. doi: 10.1016/j.ophtha.2007.03.075.

Abstract

PURPOSE

To evaluate the prevalence of refractive errors associated with age, gender, and central corneal thickness and to evaluate astigmatism in the refraction and keratometry in a randomly sampled elderly Japanese population.

DESIGN

Population-based epidemiologic survey.

PARTICIPANTS

A random sampling of residents of Tajimi, Japan, aged 40 years or older. A total of 3021 residents (participation rate, 78.1%) participated.

METHODS

Each subject underwent screening examinations including autokeratorefractometry, subjective refraction, best-corrected visual acuity, central corneal thickness measurement, intraocular pressure measurement, slit-lamp examination, fundus photography, and visual field testing.

MAIN OUTCOME MEASURES

The prevalence of myopia (spherical equivalent [SE], <-0.5 diopters [D]), high myopia (SE, <-5 D), hyperopia (SE, >0.5 D), refractive astigmatism (cylinder, >0.5 D), and anisometropia (difference in SE between eyes, >1.0 D), and the correlation of refractive errors with age, gender, and central corneal thickness. Astigmatism in the refraction and keratometry was analyzed using polar value analysis and the vector calculation method.

RESULTS

The crude prevalence of myopia, high myopia, hyperopia, refractive astigmatism in the refraction, and anisometropia was 41.8% (95% confidence interval [CI], 40.0%-43.6%), 8.2% (95% CI, 7.2%-9.2%), 27.9% (95% CI, 26.3%-29.6%), 54.0% (95% CI, 52.1%-55.8%), and 15.1% (95% CI, 13.7%-16.4%), respectively. The prevalence of myopia decreased with age up to 70 to 79 years but increased slightly in patients 80 years and older; the prevalence of hyperopia showed the opposite trend. The prevalence of astigmatism and anisometropia was higher in the older age groups. No significant gender difference was found associated with the refractive status except for keratometric readings. Polar value analysis and the vector calculation method showed a trend toward against-the-rule astigmatism with increasing age in both refractive and keratometric astigmatism, with a discrepancy between the two.

CONCLUSIONS

The overall prevalence of myopia (SE, <-0.5 diopters) was 41.8% in the study population, which is higher than that in population-based studies previously reported.

摘要

目的

评估与年龄、性别及中央角膜厚度相关的屈光不正患病率,并评估日本随机抽样老年人群中验光和角膜曲率测量中的散光情况。

设计

基于人群的流行病学调查。

参与者

日本多治见市40岁及以上居民的随机抽样。共有3021名居民参与(参与率为78.1%)。

方法

每位受试者接受筛查检查,包括自动验光、主观验光、最佳矫正视力、中央角膜厚度测量、眼压测量、裂隙灯检查、眼底照相及视野检测。

主要观察指标

近视(等效球镜度[SE],<-0.5屈光度[D])、高度近视(SE,<-5 D)、远视(SE,>0.5 D)、屈光性散光(柱镜度,>0.5 D)及屈光参差(双眼SE差值,>1.0 D)的患病率,以及屈光不正与年龄、性别及中央角膜厚度的相关性。使用极坐标值分析和矢量计算方法分析验光和角膜曲率测量中的散光情况。

结果

近视、高度近视、远视、验光中的屈光性散光及屈光参差的粗患病率分别为41.8%(95%置信区间[CI],40.0%-43.6%)、8.2%(95% CI,7.2%-9.2%)、27.9%(95% CI,26.3%-29.6%)、54.0%(95% CI,52.1%-55.8%)及15.1%(95% CI,13.7%-16.4%)。近视患病率在70至79岁之前随年龄增长而降低,但在80岁及以上患者中略有升高;远视患病率则呈现相反趋势。散光和屈光参差患病率在老年组中较高。除角膜曲率读数外,未发现屈光状态与性别存在显著差异。极坐标值分析和矢量计算方法显示,在验光和角膜曲率测量散光中,随着年龄增长均有逆规散光趋势,且两者之间存在差异。

结论

研究人群中近视(SE,<-0.5屈光度)的总体患病率为41.8%,高于先前报道的基于人群的研究结果。

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