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病毒学:猫和雪貂的SARS病毒感染

Virology: SARS virus infection of cats and ferrets.

作者信息

Martina Byron E E, Haagmans Bart L, Kuiken Thijs, Fouchier Ron A M, Rimmelzwaan Guus F, Van Amerongen Geert, Peiris J S Malik, Lim Wilina, Osterhaus Albert D M E

机构信息

Institute of Virology, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands.

出版信息

Nature. 2003 Oct 30;425(6961):915. doi: 10.1038/425915a.

DOI:10.1038/425915a
PMID:14586458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7094990/
Abstract

UNLABELLED

The reservoir of the coronavirus isolated from patients with severe acute respiratory syndrome (SARS) is still unknown, but is suspected to have been a wild animal species. Here we show that ferrets () and domestic cats () are susceptible to infection by SARS coronavirus (SCV) and that they can efficiently transmit the virus to previously uninfected animals that are housed with them. The observation that these two distantly related carnivores can so easily be infected with the virus indicates that the reservoir for this pathogen may involve a range of animal species.

SUPPLEMENTARY INFORMATION

The online version of this article (doi:10.1038/425915a) contains supplementary material, which is available to authorized users.

摘要

未标注

从严重急性呼吸综合征(SARS)患者中分离出的冠状病毒的宿主仍不清楚,但怀疑是一种野生动物。我们在此表明,雪貂()和家猫()易受SARS冠状病毒(SCV)感染,并且它们能够有效地将病毒传播给与它们共同饲养的先前未感染的动物。这两种亲缘关系较远的食肉动物如此容易感染该病毒的观察结果表明,这种病原体的宿主可能涉及一系列动物物种。

补充信息

本文的在线版本(doi:10.1038/425915a)包含补充材料,授权用户可获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b91e/7094990/eedd40b04ba9/41586_2003_Article_BF425915a_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b91e/7094990/eedd40b04ba9/41586_2003_Article_BF425915a_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b91e/7094990/eedd40b04ba9/41586_2003_Article_BF425915a_Fig1_HTML.jpg

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